Article Sidebar

Download
PDF (Bahasa Indonesia)
Statistic
Read Counter : 193 Download : 194

Downloads

Download data is not yet available.

Main Article Content

Abstract

Pare leaves (Momordica charantia L.) have many health benefits. Leaves pare (M.chrantia L.) are a trusted herb that is used as an antibacterial plant. N-hexane fraction of pare leaves(S. epidermidis). The purpose of this study is to identify the secondary metabolite compounds found in the n-hexane fraction of ethanol extract 96% of pare leaves (M.charantia L.) and to find out the N-hexane fractions of etanol 96% pare leaves (M.charantia L.) in inhibiting S.epidermidis bacteria. The type of research is experimental. The leaf extraction process uses maseration with 96% ethanol solvent and fraxination using n-hexane solvent. Phytochemical screening tests include flavonoids, alkaloids, saponins, steroids/terpenoids, phenols and tannins. The antibacterial activity carried out using well method with concentration of 1%, 2%, 3% and 4%. The results of this study showed that a fraction of n-hexane ethanol extract 96% of the leaf (M.charantia L.) contained flavonoid, alkaloid and steroid compounds. The n-hexane fraction ethanol extract 96% leaf (M.charantia L.) has antibacterial activity in inhibiting the S.epidermidis bacteria in the weak to strong category. Based on the results, it can be concluded that the fraction n-hexane ethanol extract 96% of the leaf (Momordica charantia L.) is able to inhibit the bacteria S.epidermidis at all concentrations.

Keywords

Antibacterial Pare Leaves Momordica charantia L. Staphylococcus epidermidis

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biographies

Rabiatul Munawarah, Universitas Borneo Lestari

Program Studi Sarjana Farmasi, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia

Putri Kartika Sari, Universitas Borneo Lestari

Program Studi Diploma Tiga Analis Kesehatan, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia

Eka Fitri Susiani, Universitas Borneo Lestari

Program Studi Sarjana Farmasi, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia
How to Cite
Munawarah, R., Sari, P. K., & Susiani, E. F. (2023). Uji Aktivitas Antibakteri Fraksi N-Heksana Ekstrak Etanol 96% Daun Pare (Momordica charantia L.) Terhadap Bakteri Staphylococcus epidermidis. Borneo Journal of Pharmascientech, 7(2), 79-85. https://doi.org/10.51817/bjp.v7i2.494
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX

References

  1. Anggreany, R. T., Rahmawati, I., & Leviana, F. 2020. Uji Antibakteri Ekstrak Dan Fraksi Herba Ciplukan (Physalis angulata L.) Untuk Mengatasi Infeksi Staphylococcus epidermidis Selama Persalinan. Dinamika Kesehatan: Jurnal Kebidanan Dan Keperawatan, 11(1): 253-263.
  2. Annisa, R., Amir, M., & Kuncoro, H. (2017). Toxicity Study Of Pare Leaf Extracts (Momordica charantia L.) to culex pipien mosquito larvae. Journal of Islamic Pharmacy, 2(2), 13-24.
  3. Basir, H & Trie Milda. 2020. Uji Aktivitas Ekstrak Etanol Daun Pare Hijau (Momordica charantia L.) Terhadap Staphylococcus epidermidis. Jurnal Kesehatan Yamasi Makassar, 4(2).
  4. Birla, D. 2016. Evaluation Of Antibacterial Activity Of Momordica Charantia. Pharmatutor, 4(11): 37-40.
  5. Fitriyanti, F., Abdurrazaq, A., & Nazarudin, M. 2019. Uji efektivitas antibakteri ekstrak etil asetat bawang dayak (Eleutherine palmifolia Merr) terhadap Staphylococcus aureus dengan metode sumuran. Jurnal Ilmiah Manuntung, 5(2): 174-182.
  6. Fitriyanti., Syaid Nofal Assegaf &Karunita Ika Astut. 2022. Uji daya hambat ekstrak etanol 96% daun jeruk purut (citrus hystrix d.c. ) terhadap propionibacterium acnes. Borneo Journal Of Pharmascientech ; Vol 06 No 02.
  7. Fransiska, N. A., Masyrofah, D., Marlian, H., Sakina, I. V. & Tyasna, P. S. 2021. Identifikasi Senyawa Terpenoid dan Steroid Pada Beberapa Tanaman Menggunakan Pelarut n-heksana. Jurnal Health Sains. 2(6): 733-741.
  8. Novaryatiin, Susi, Pratomo, Guntur & yunari, 2018. Uji Daya Hambat Ekstrak Etanol Daun Sirih Hijau (Piper betle L.) terhadap Bakteri S. aureus. Journal of Universitas Muhammidayah Palangkaraya.
  9. Pakadang, S. R & Salim 2020. Pengaruh Ekstrak Daun Pare (Momordica charantia L.) Terhadap Pertumbuhan Streptococcus pneumonia, Staphylococcus epidermidis, Staphylococcus aureus Dan Klebsiella pneumonia Penyebab Infeksi Saluran Pernapasan Akut. Media Farmasi, 16(2), 207-214.
  10. Pariury, J. A., Herman, J. P. C., Rebecca, T., Veronica, E., & Arijana, I. G. K. N. 2021. Potensi Kulit Jeruk Bali (Citrus maxima Merr) Sebagai Antibakteri Propionibacterium Acne Penyebab Jerawat. Hang Tuah Medical Journal, 19(1), 119-131.
  11. Puspasari., Heny.,Suhaimi, S., Husnani, H., & Krismonika, I. F. 2020. Uji Daya Hambat Ekstrak Kental Daun Kratom (Mitragyna Speciosa Korth) Terhadap Pertumbuhan Bakteri Staphylococcus epidermidis Sebagai penyebab Jerawat. Medical Sains: Jurnal Ilmiah Kefarmasian, 4(2), 87-94.
  12. Putriyana, D., Tivani, I., & Purgiyanti, P. 2021. Uji Aktivitas Antibakteri Sediaan Lotion Ekstrak Daun Pare (Momordica charantia L.) Terhadap Bakteri Staphylococcus Aureus. Skripsi. Politeknik Harapan Bersama Tegal, Tegal.
  13. Rini, A. A., Supriatno., & Rahmatan, H. 2017. Skrining Fitokimia Dan Uji Antibakteri Ekstrak Etanol Buah Kawista (Limonia acidissima L.) Dari Daerah Kabupaten Aceh Besar Terhadap Bakteri Escherichia coli. Jurnal Ilmiah Fakultas Keguruan dan Ilmu Pendidikan Unsyiah. 2(1): 1-12.
  14. Rizqiana, K., & Pambudi, D. B. 2021. Uji Aktivitas Antibakteri Ekstrak Etanol Daun Pare (Momordica charantia L.) Terhadap Bakteri Staphylococcus aureus Atcc 25923. In Prosiding Seminar Nasional Kesehatan (Vol. 1, Pp. 1598-1604).
  15. Rosidah, M. S., Lambui, O., & Suwastika, I. N. 2018. Ekstrak Daun Tumbuhan Macaranga tanarius (L.) MA Menghambat Laju Pertumbuhan Bakteri Staphylococcus epidermidis. Natural Science: Journal of Science and Technology, 7(1).
  16. Rusmin, R., & Pine, A. T. D. 2020. Standardisasi Mutu Fisik Ekstrak Etanol Daun Pare Hijau (Momordica charantia L.). Jurnal Kesehatan Yamasi Makassar, 4(1).
  17. Septiningsih, R., Sutanto, S., & Indriani, D. 2017. Aktivitas Antioksidan Ekstrak Etanol Daun, Buah Dan Biji Pare (Momordica charantia L). FITOFARMAKA: Jurnal Ilmiah Farmasi, 7(1), 4-12.
  18. Utami, Ayu Bintang, G., Sudarmanto & Merta. 2015. Perbedaan Zona Hambat Pertumbuhan Staphylococcus aureus Pada Perbedaan Konsentrasi Perasan Daun Pare Secara In Vitro. Meditory Journal. 3(2) : 1-5.
  19. Yusriyani, Parung D.S. 2019. Uji Aktivitas Antibakteri Ekstrak Daun Pare (Momordica charantia L) Terhadap Bakteri Pseudomonas aeruginosa. Jurnal Kesehatan Yamasi Makassar, 3 (1)