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Abstract

Pare leaves (Momordica charantia L.) have many health benefits. Leaves pare (M.chrantia L.) are a trusted herb that is used as an antibacterial plant. N-hexane fraction of pare leaves(S. epidermidis). The purpose of this study is to identify the secondary metabolite compounds found in the n-hexane fraction of ethanol extract 96% of pare leaves (M.charantia L.) and to find out the N-hexane fractions of etanol 96% pare leaves (M.charantia L.) in inhibiting S.epidermidis bacteria. The type of research is experimental. The leaf extraction process uses maseration with 96% ethanol solvent and fraxination using n-hexane solvent. Phytochemical screening tests include flavonoids, alkaloids, saponins, steroids/terpenoids, phenols and tannins. The antibacterial activity carried out using well method with concentration of 1%, 2%, 3% and 4%. The results of this study showed that a fraction of n-hexane ethanol extract 96% of the leaf (M.charantia L.) contained flavonoid, alkaloid and steroid compounds. The n-hexane fraction ethanol extract 96% leaf (M.charantia L.) has antibacterial activity in inhibiting the S.epidermidis bacteria in the weak to strong category. Based on the results, it can be concluded that the fraction n-hexane ethanol extract 96% of the leaf (Momordica charantia L.) is able to inhibit the bacteria S.epidermidis at all concentrations.

Keywords

Antibacterial Pare Leaves Momordica charantia L. Staphylococcus epidermidis

Article Details

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biographies

Rabiatul Munawarah, Universitas Borneo Lestari

Program Studi Sarjana Farmasi, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia

Putri Kartika Sari, Universitas Borneo Lestari

Program Studi Diploma Tiga Analis Kesehatan, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia

Eka Fitri Susiani, Universitas Borneo Lestari

Program Studi Sarjana Farmasi, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia

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