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Abstract

The Sungkai plant (P. canescens Jack) is known to have medicinal properties in the traditional treatment of skin diseases. The aim of this research is to identify groups of phytochemical compounds contained in the methanol extract from Sungkai leaves, as well as evaluate the ability of the methanol extract to inhibit the growth of P. acnes bacteria. In the first stage, phytochemical screening was carried out from the methanol extract of Sungkai leaves. The results of this screening show that the methanol extract of Sungkai leaves contains alkaloids, flavonoids, phenols, triterpenoids and tannins. In the antibacterial activity test, the diffusion method with the well technique was used at extract concentrations of 1%, 5%, 10%, 15% and 20%. As a comparison, the positive control used clindamycin with a concentration of 2 µg/disk, while the negative control used Na-CMC with a concentration of 0.5%. The results of the antibacterial activity test showed that at a concentration of 1%, the methanol extract of Sungkai leaves had an inhibition zone with moderate intensity. However, at a concentration of 20% as well as in the positive control clindamycin with a concentration of 2 µg/disc, there was a stronger zone of inhibition. Thus, these findings indicate that methanol extract from Sungkai leaves has the potential to inhibit the growth of P. acnes, which is often associated with skin problems. The phytochemical compounds contained in this extract can be the basis for potential development in natural-based skin

Keywords

Sungkai Leaf Methanol Well Diffusion Antibacterial

Article Details

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biographies

Shelin Shelin, Universitas Borneo Lestari

Program Studi Sarjana Farmasi, Fakultas Farmasi, Universitas Borneo Lestari, Banjarbaru, Indonesia

Fitriyanti Fitriyanti, Universitas Borneo Lestari

Program Studi Sarjana Farmasi, Fakultas Farmasi, Universitas Borneo Lestari, Banjarbaru, Indonesia

Muhammad Saufi , Universitas Borneo Lestari

Program Studi Sarjana Managemen, Fakultas Ilmu Sosial dan Humaniora, Universitas Borneo Lestari, Banjarbaru

References

  1. Ariani, N., & Niah, R. (2020). Uji Aktivitas Antibakteri Ekstrak Etanol Kulit Pisang Kepok Mentah Secara in Vitro. Jurnal Ilmiah Manuntung, 5(2), 161. https://doi.org/10.51352/jim.v5i2.270
  2. Bramono, S. L. S. M. ., & Indriatmi, W. (2015). Ilmu Penyakit Kulit dan Kelamin. Edisi ke-7. Fakultas Kedokteran Universitas Indonesia, Jakarta.Cho, S., J & Jinhyun K. Factors Associated With Nonadherence to Antihypertensive Medication, Vol 16, Tahun 2014, Hal 461-467.
  3. Dewa, I., Eka, A., Putri, W., Ayu, G., Ratnayanti, D., Sugiritama, W., Kamasan, G., & Arijana, N. (2021). Analisis Fitokimia Nira Aren dan Tuak Aren (Arenga pinnata (Wurmb) Merr.). Juni, 10(6), 2021. https://ojs.unud.ac.id/index.php/eum
  4. Febrianti, D. R., Susanto, Y., Niah, R., & Latifah, S. (2019). Aktivitas Antibakteri Minyak Atsiri Kulit Jeruk Siam Banjar (Citrus reticulata) Terhadap Pertumbuhan Pseudomonas aeruginosa. Jurnal Pharmascience, 6(1), 10. https://doi.org/10.20527/jps.v6i1.6070
  5. Fitriyanti, F., Qalbiyah, S., & Sayakti, P. (2020). Identifikasi Kulit Batang Kalangkala (Litsea Angulata Bi) Secara Makroskopik, Mikroskopik, Dan Skrining Fitokimia. Parapemikir : Jurnal Ilmiah Farmasi, 9(2), 1–9. https://doi.org/10.30591/pjif.v9i2.1832
  6. Hafsari, A. R., Tri, C., Toni, S., & Rahayu, I. L. (2015). Uji Aktivitas Antibakteri Daun Beluntas. Uji Aktivitas Antibakteri Ekstrak Daun Beluntas (Pluchea Indica (L.) LESS. ) Terhadap Propionibacterium Acnes Penyebab Jerawat, Journal 9(1), 142–161.
  7. Ibrahim, A., & Kuncoro, H. (2012). Identifikasi Metabolit Sekunder Dan Aktivitas Antibakteri Ekstrak Daun Sungkai (Peronema canescens jack.) Terhadap Beberapa Bakteri Patogen. Journal Of Tropical Pharmacy And Chemistry, 2(1), 8–18. https://doi.org/10.25026/jtpc.v2i1.43
  8. Indriani, O., F.Awalul., & Trio. (2019). Pengaruh Ekstrak Dan Fraksi Daun Karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.) Terhadap Pertumbuhan Bakteri Escherichia coli. Jurnal Palembang, 4(3).
  9. Kumalasari, E., Susanto, Y., Rahmi, M. Y., & Febrianty, R. D. (2019). Pengaruh Pemberian Ekstrak Etanol Daun Ramania (Bouea macrophylla Griffith) Terhadap Penurunan Kadar Gula Darah Mencit Putih (Mus muscullus) Yang Diinduksi Aloksan. Journal Current Pharmaceutical Sciences, 2(2), 2598–2095.
  10. Mengga, C., Rampe, M., & Sangande, F. (2022). Uji Efektivitas Antibakteri Ekstrak Daun Binahong (Anredera cordifolia (Tenore) Steenis) Terhadap Bakteri Staphylococcus aureus. Biofarmasetikal Tropis,5(1),60–65. https://doi.org/10.55724/jbiofartrop.v5i1.370
  11. Ngajow, M., Abidjulu, J., & Kamu, V. S. (2013). Pengaruh Antibakteri Ekstrak Kulit Batang Matoa (Pometia pinnata) terhadap Bakteri Staphylococcus aureus secara In vitro. Jurnal MIPA, 2(2),128. https://doi.org/10.35799/jm.2.2.2013.3121
  12. Putrajaya, F., Hasanah, N., & Kurlya, A. (2019). Daya Hambat Ekstrak Etanol Daun Suruhan (Peperomia pellucida l.) Terhadap Pertumbuhan Bakteri Penyebab Jerawat (Propionibacterium acnes) Dengan Metode Sumur Agar. Edu Masda Journal, 3(2), 123. https://doi.org/10.52118/edumasda.v3i2.34
  13. Radam, R., Soendjoto, M. A., & Prihatiningtyas, E. (2016). Pemanfaatan Tumbuhan Yang Berkhasiat Obat Oleh Masyarakat Di Kabupaten Tanah Bumbu, Kalimantan Selatan Utilization of Medicinal Plants by Community in Tanah Bumbu Regency , South Kalimantan. Prosiding Seminar Nasional Lahan Basa, 2, 486–492.
  14. Susanti, H. D., Arfamaini, R., Sylvia, M., Vianne, A., D, Y. H., D, H. L., Muslimah, Abraham, C., Sheeran, P., Adiyoso, W., Wilopo, W., Brossard, D., Wood, W., Cialdini, R., Groves, R. M., Chan, D. K. C., Zhang, C. Q., & Josefsson, K. W., ... Aryanta, I. R. (2017). Skrining Fitokimia Senyawa Metabolit Sekunder Dari Esktrak Etanol Buah Delima (Punica granatum L.) Dengan Metode Uji Warna. , 4(1), 724–732. Jurnal Keperawatan. Universitas Muhammadya Malang, 4(1), 724–732.
  15. Tendean, I. K., Silintowe Kenta, Y., & Mulyani, S. (2017). Uji Ekstrak Etanol Daun Talas (Colocasia Escuenta (L.) Schott.) Terhadap Gambaran Hispatologi Pankreas Tikus Putih Jantan (Rattus norvegicus) Hiperkolestrolemia diabetes. Journal.Ags, 2, 1558.
  16. Wahidah, S. W., Fadhilah, K. N., Nahhar, H., Afifah, S. N., & Sri, N. (2021). Uji Skrining Fitokimia dari Amilum Familia Zingiberaceae. Jurnal Buana Farma, 1(9), 1–4.