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Abstract

Tuberculosis (TB) requires regular treatment over an extended period. Adverse drug reactions (ADRs) to anti-tuberculosis drugs (ATDs) may pose challenges during therapy; therefore, patient monitoring and counseling are essential. This study aimed to analyze the association between the severity of ATD adverse effects and medication adherence among patients with pulmonary TB at Tumbang Sangai Primary Health Center. An analytical observational study with a cross-sectional design was conducted. A total of 32 patients were recruited using accidental sampling. Questionnaires assessing TB drug adverse effects and medication adherence were utilized as research instruments. The results showed that 26 patients (81.3%) experienced severe adverse effects, 3 (9.4%) experienced moderate adverse effects, and 3 (9.4%) experienced mild adverse effects. Regarding medication adherence, 24 patients (75.0%) were classified as adherent, while 8 (25.0%) were classified as non-adherent. Notably, 81.3% of patients experienced severe adverse effects, although the overall medication adherence rate was 75.0%. Statistical analysis using the Fisher-Freeman-Halton exact test revealed a significant association between ATD adverse effects and medication adherence (p = 0.035; p < 0.05). In conclusion, a significant association was found between ATD adverse effects and medication adherence among patients with pulmonary TB at Tumbang Sangai Primary Health Center.

Keywords

Side Effects Compliance Pulmonary TB

Article Details

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Author Biographies

Guntur Kurniawan, Program Studi Sarjana Farmasi., Fakultas Farmasi, Universitas Borneo Lestari, Kota Banjarbaru

Program Studi Sarjana Farmasi., Fakultas Farmasi, Universitas Borneo Lestari, Kota Banjarbaru

Evy Dharmayanti, Program Studi Sarjana Farmasi., Fakultas Farmasi, Universitas Borneo Lestari, Kota Banjarbaru

Program Studi Sarjana Farmasi., Fakultas Farmasi, Universitas Borneo Lestari, Kota Banjarbaru

Helmina Wati, Program Studi Pendidikan Profesi Apoteker, Fakultas Farmasi, Universitas Borneo Lestari

Program Studi Pendidikan Profesi Apoteker, Fakultas Farmasi, Universitas Borneo Lestari

Weldy Weldy, Program Studi Sarjana Farmasi., Fakultas Farmasi, Universitas Borneo Lestari, Kota Banjarbaru

Program Studi Sarjana Farmasi., Fakultas Farmasi, Universitas Borneo Lestari, Kota Banjarbaru
How to Cite
Kurniawan, G., Dharmayanti, E., Wati, H., & Weldy, W. (2026). Hubungan Tingkat Keparahan Efek Samping Obat Anti Tuberkulosis (OAT) Dengan Kepatuhan Minum Obat Pada Pasien Tb Paru Di Puskesmas Tumbang Sangai. Borneo Journal of Pharmascientech, 10(2), 336-346. https://doi.org/10.59053/bjp.v10i2.808
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