Main Article Content

Abstract

Diabetes mellitus is a chronic disease that requires long term therapy. This can lead to complications in type 2 diabetes mellitus. Complications can be avoided by regulating blood sugar levels through various pharmacological and non pharmacological activities. Compliance with the medication use is one of the most crucial aspects in achieving the desired treatment results. As a measuring tool to evaluate the level of adherence in type 2 diabetes mellitus patients, the Probabilistic Medication Adherence Scale (ProMAS)questionnaire was used. This tudy aims to evaluate the relationship between adherence levels and HbA1c levels in patients with type 2 diabetes mellitus. This study utilized a cross sectional desain analysis approach. Sampling was carried out using a purposive. The total sample used in this study was 35 respondents. Compliance assessment data will be processed using univariate tests and pearson chi square. From the research conducted on 35 respondents, it was found that there were 9 people (25.71%) in the low compliance category, 4 people (11.43%) with medium-low compliance, 14 people (40%) with medium-high compliance, and there wewe 8 people (22.86%) with high compliance. From the analysis conducted on the chi square tests to assess the relationship between respondent characteristics and compliance, it showed no significant relationship between the two variables (p-value > 0,05). Meanwhile, in the analysis of the relationship between compliance and HbA1c levels, a p-value of 0,003 was obtained, indicating a significant relationship between the two variables. Compliance with treatment affects HbA1c levels.

Keywords

DM Tipe 2 Adherensi HbA1c Kuesioner ProMAS

Article Details

Author Biographies

Dian Handayani, Program Studi Diploma Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu

Program Studi Diploma Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu

Ikhsan Ikhsan, Program Studi Diploma Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu

Program Studi Diploma Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu

Galuh Sekar Salindri, Program Studi Sarjana Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu

Program Studi Sarjana Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu

Halwa Balqis Mahardika, Program Studi Sarjana Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu

Program Studi Sarjana Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu

David Andianrysky Siallagan, Program Studi Diploma Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu

Program Studi Diploma Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu
How to Cite
Handayani, D., Ikhsan, I., Salindri, G. S., Mahardika, H. B., & Siallagan, D. A. (2026). Hubungan Tingkat Adherensi Terhadap Kadar HbA1c Pada Pasien Diabetes Melitus Tipe 2. Borneo Journal of Pharmascientech, 10(2), 357-365. https://doi.org/10.59053/bjp.v10i2.758

References

  1. Abebaw, M., Messele, A., Hailu, M., & Zewdu, F. (2016). Adherence and Associated Factors towards Antidiabetic Medication among Type II Diabetic Patients on Follow-Up at University of Gondar Hospital, Northwest Ethiopia. Advances in Nursing, 2016, 1–7. https://doi.org/10.1155/2016/8579157
  2. ADA. (2022). Disclosures: Standards of Medical Care in Diabetes-2022. Diabetes Care, 45(January), S256–S258. https://doi.org/10.2337/dc22-Sdis
  3. Al Assaf, S., Zelko, R., & Hanko, B. (2022). The Effect of Interventions Led by Community Pharmacists in Primary Care for Adults with Type 2 Diabetes Mellitus on Therapeutic Adherence and HbA1c Levels: A Systematic Review. International Journal of Environmental Research and Public Health, 19, 1–16. https://doi.org/10.3390/ijerph19106188
  4. Anshari, A. F., Ichsan, B., & Cholisoh, Z. (2023). Hubungan Kepatuhan Minum Obat terhadap HbA1C dan Kualitas Hidup Pasien Diabetes di RSI Purwodadi. JPSCR: Journal of Pharmaceutical Science and Clinical Research, 3, 317–328. https://doi.org/10.20961/jpscr.v8i3.73753
  5. Baharudin, A., Ambak, R., Othman, F., Michael, V., Cheong, S. M., Nor, N. A., Abdul Aziz, N. S., Mohd. Sallehuddin, S., Ganapathy, S. S., Palaniveloo, L., & He, F. J. (2021). Knowledge, attitude and behaviour on salt intake and its association with hypertension in the Malaysian population: findings from MyCoSS (Malaysian Community Salt Survey). Journal of Health, Population and Nutrition, 40(Suppl 1), 1–9. https://doi.org/10.1186/s41043-021-00235-0
  6. Chantzaras, A., & Yfantopoulos, J. (2022). Association between medication adherence and health-related quality of life of patients with diabetes. Hormones, 21, 691–705. https://doi.org/10.1007/s42000-022-00400-y
  7. Eze, U. I. H., Akhumi, T. F., Iheanacho, C. O., & Saka, S. A. (2022). Drug therapy and medication adherence in type 2 diabetes in a care facility: A cross sectional survey. Exploratory Research in Clinical and Social Pharmacy, 8, 1–5. https://doi.org/10.1016/j.rcsop.2022.100200
  8. Hamarno, R., Nurdiansyah Z, M., & Toyibah, A. (2016). Hubungan Antara Kepatuhan Kontrol Dengan Terjadinya Komplikasi Kronis Pada Penderita Diabetes Melitus Tipe 2 Di Puskesmas Janti Kota Malang. Jurnal Keperawatan Universitas Muhammadiyah Malang, 7(2), 126–134.
  9. Haryati, A. I., & Tyas, T. A. W. (2022). Perbandingan Kadar HbA1c pada Pasien Diabetes Melitus Tipe 2 yang Disertai Hipertensi dan Tanpa Hipertensi di Rumah Sakit Umum Daerah Duri, Mandau, Bengkalis, Riau. Jurnal Kedokteran Dan Kesehatan, 18(1), 33. https://doi.org/10.24853/jkk.18.1.33-40
  10. Hasanah, L., Ariyani, H., & Hartanto, D. (2022). Hubungan Kualitas Hidup Pasien Diabetes Melitus Tipe 2 Dengan Kepatuhan Minum Obat Di RSUD Ulin Banjarmasin. Journal of Current Pharmaceutical Sciences, 6(1), 581–589.
  11. Hasina, R., Probosuesno, & Wiedyaningsih, C. (2014). Hubungan Tingkat Kepatuhan, Kepuasan Terapi dengan Kualitas Hidup Pasien Usia Lanjut Diabetes Melitus Tipe 2. Jurnal Manajemen Dan Pelayanan Farmasi, 4(4), 251–256.
  12. Haskani, N. H. M., Goh, H. P., Wee, D. V. T., Hermansyah, A., Goh, K. W., & Ming, L. C. (2022). Medication Knowledge and Adherence in Type 2 Diabetes Mellitus Patients in Brunei Darussalam: A Pioneer Study in Brunei Darussalam. International Journal of Environmental Research and Public Health, 19, 1–13. https://doi.org/10.3390/ijerph19127470
  13. Kemenkes. (2019). Buku Pedoman Manajemen Penyakit Tidak Menular. In Kementerian Kesehatan RI.
  14. Kleppe, M., Lacroix, J., Ham, J., & Midden, C. (2015). The development of the ProMAS: A probabilistic medication adherence scale. Patient Preference and Adherence, 9, 355–367. https://doi.org/10.2147/PPA.S76749
  15. Loanda, E., Margaret, A. L., & Hidayat, J. (2016). Asupan Gula Harian Dari Bahan-Bahan Pelengkap Masakan. Majalah Kedokteran Andalas, 39(1), 21–27. https://doi.org/10.22338/mka.v39.i1.p21-27.2016
  16. Murwanashyaka, J. de D., Ndagijimana, A., Biracyaza, E., Sunday, F. X., & Umugwaneza, M. (2022). Non-adherence to medication and associated factors among type 2 diabetes patients at Clinique Medicale Fraternite, Rwanda: a cross-sectional study. BMC Endocrine Disorders, 22(219), 1–14. https://doi.org/10.1186/s12902-022-01133-0
  17. Pratiwi, F. I., & Widayati, A. (2021). Pengaruh Intervensi Tenaga Kesehatan terhadap Kepatuhan Minum Obat pada Pasien Diabetes Mellitus Tipe 2 di Indonesia: Kajian Literatur. Jurnal Sains Farmasi & Klinis, 8(2), 107–115. https://doi.org/10.25077/jsfk.8.2.107-115.2021
  18. Puspitasari, A. W. (2012). Analisis Efektivitas Pemberian Booklet Obat Terhadap Tingkat Kepatuhan Ditinjau dari Kadar Hemoglobin Terglikasi (HbA1C) dan Morisky Medication Adherence Scale (MMAS)-8 Pada Pasien Diabetes Melitus Tipe 2 di Puskesmas Bakti Jaya Kota Depok. In Universitas Indonesia.
  19. Saudi, R. A., Abbas, R. A., Nour-Eldein, H., & Ahmed, H. A. S. (2022). Illness perception, medication adherence and glycemic control among primary health-care patients with type 2 diabetes mellitus at Port Said City, Egypt. Diabetology International, 13, 522–530. https://doi.org/10.1007/s13340-021-00567-6
  20. Widodo, H. A. P. (2017). HUBUNGAN ANTARA KEPATUHAN DIET DENGAN PERUBAHAN KADAR GULA DARAH PADA PASIEN DIABETES MELITUS YANG BEROBAT KE PUSKESMAS TAWANGREJO KOTA MADIUN. In STIKES BHAKTI HUSADA MULIA MADIUN.