Main Article Content

Abstract

The 96% ethanol extract of green binahong leaves contains flavonoid compounds with potential activity as a sunscreen. Flavonoid compounds have been identified via FTIR and show part of this functional group. in the form of aliphatic C-H, C=O, C=C, and C-O. This research aims to determine the stability of the physical and chemical quality of o/w type sunscreen lotion and its activity as a sunscreen in vitro using a UV-vis spectrophotometer. The extract is obtained using the ethanol maceration method and then formulated into lotion and o/w cream and tested for physical and chemical stability and tested for SPF in vitro with a spectrophotometer. The results of this research indicate that the o/w lotion formula is stable during the storage period of 6 cycles. The increase in the diameter value of spreadability and sticking time is influenced by storage factors, the longer the preparation is stored, the viscosity will decrease. Sunscreen activity calculated using the Mansur equation shows that the SPF value at 0.5%, 2.5% and 4.5% levels of green binahong leaf extract is 3.37; 8.25 ; 8.93. The sunscreen lotion preparation of 96% ethanol extract of green binahong leaves is stable during storage and has activity as a sunscreen.

Keywords

extract of green binahong leaves FTIR Flavonoids Lotion o/w Stability SPF

Article Details

Author Biographies

Deby Nurluthfiana, Program Studi Farmasi Universitas Muhammadiyah Ahmad Dahlan Cirebon

Program Studi Farmasi Universitas Muhammadiyah Ahmad Dahlan Cirebon

Teguh Adiyas Putra, Program Studi Farmasi Universitas Muhammadiyah Ahmad Dahlan Cirebon

Program Studi Farmasi Universitas Muhammadiyah Ahmad Dahlan Cirebon

Ade Irawan, Program Studi Farmasi Universitas Muhammadiyah Ahmad Dahlan Cirebon

Program Studi Farmasi Universitas Muhammadiyah Ahmad Dahlan Cirebon
How to Cite
Nurluthfiana, D., Adiyas Putra, T., & Irawan, A. (2025). Profil Senyawa Fitokimia Menggunakan Metode FTIR dan Pengujian Nilai SPF Secara In Vitro Formulasi Lotion O/W Ekstrak Etanol 96% Daun Binahong Hijau. Borneo Journal of Pharmascientech, 9(1), 35-44. https://doi.org/10.59053/bjp.v9i1.546

References

  1. Apriyani, T. (2021). UJI AKTIVITAS ANTIOKSIDAN & SPF ( Sun Protection Factor ) EKSTRAK POLAR & NON POLAR DAUN KEDONDONG ( Spondias dulcis Parkinson ) SECARA IN VITRO PROGRAM STUDI S1 FARMASI FAKULTAS FARMASI.
  2. Armadany, F. I., Ode, W., Musnina, S., & Wilda, U. (2019). Formulasi dan Uji Stabilitas Lotion Antioksidan dari Ekstrak Etanol Rambut Jagung ( Zea mays L .) sebagai Antioksidan dan Tabir Surya. Pharmauho, 5(April), 1–5.
  3. Ashari, S., Hanin, H., Ida, F., & Sholichah, R. (2020). Potensi senyawa flavonoid dalam tanaman sebagai lotion tabir surya. Proceedings National Conference PKM Center, 1(1), 164–166.
  4. Fitraneti, E., Rizal, Y., Riska Nafiah, S., Primawati, I., & Ayu Hamama, D. (2024). Pengaruh Paparan Sinar Ultraviolet terhadap Kesehatan Kulit dan Upaya Pencegahannya : Tinjauan Literatur. Scientific Journal, 3(3), 185–194. https://doi.org/10.56260/sciena.v3i3.147
  5. Gamah, Nastiti, K., & Arizky, S. (2023). PROFIL SENYAWA ALKALOID DENGAN METODE SPEKTROSKOPI INFRAMERAH ( FTIR ) DAN PENETAPAN KADAR TOTAL ALKALOID DARI EKSTRAK DAUN JARAK PAGAR ( Jaropha Curcas . L ). Journal of Pharmaceutical Care and Sciences, 4828, 168–181. https://doi.org/10.33859/jpcs.v4i1.476
  6. Husni, P., Ruspriyanti, Y., & Hasanah, U. (2021). Formulasi dan uji stabilitas fisik sediaan. 9(2).
  7. Putri, D. (2019). Formulasi dan Evaluasi Losion Tabir Surya Ekstrak Daun Stevia ( Stevia rebaudiana Bertoni M ). 6(1), 32–36.
  8. Ramadhianti, S. (2020). ISOLASI DAN UJI TOKSISITAS SENYAWA FLAVONOID DARI DAUN BINAHONG (Anredera cordifolia) DENGAN METODE Brine Shrimp salina Leach MENGGUNAKAN EKSTRAKSI ULTRASONIK.
  9. Rusmin. (2021). FORMULASI DAN UJI STABILITAS SEDIAAN KERIM EKSTRAK RIMPANG IRIS (Iris pallida Lamk.) MENGGUNAKAN EMULGATOR ANIONIK DAN NOIONIK. Jurnal Kesehatan Yamasi Makassar, 5(2), 50–58.
  10. Sapra, A., Riski, R., & Jamila, B. (2020). EVALUASI KRIM ANTIOKSIDAN SOLID LIPID MICROPARTICLE EKSTRAK ETANOL DAUN KERSEN (MUNTINGIA CALABURA L.). XV(1), 31–37.
  11. Sari, D. E. M., & Fitrianingsih, S. (2020). Analisis Kadar Nilai Sun Protection Factor (SPF) pada Kosmetik Krim Tabir Surya yang Beredar di Kota Pati Secara In Vitro. Cendekia Journal of Pharmacy, 4(1), 69–79. https://doi.org/10.31596/cjp.v4i1.81
  12. Sari, N., Samsul, E., & Narsa, A. C. (2021). Pengaruh Trietanolamin pada Basis Krim Minyak dalam Air yang Berbahan Dasar Asam Stearat dan Setil Alkohol. Proceeding of Mulawarman Pharmaceuticals Conferences, 70–75.
  13. Septyowardani, D. T., & Parmadi, A. (2021). Formulasi Krim Tabir Surya Dan Penentuan Nilai SPF Ekstrak Etanol Daun Binahong (Anredera cardifolia (Tenore) Steenis). Indonesian Journal on Medical Science, 8(2). https://doi.org/10.55181/ijms.v8i2.319
  14. Sukarti, Yulianti, K., & Illing, I. (2020). CONTENT ANALYSIS AND IDENTIFICATION OF FUNCTIONAL GROUPS OF FLAVONOID COMPOUNDS FROM CHLOROFORM EXTRACT OF AKAR BULU LEAF ( Merremia vitifolia ) ANALISIS KADAR DAN IDENTIFIKASI GUGUS FUNGSI SENYAWA FLAVONOID DARI EKSTRAK KLOROFORM DAUN AKAR BULU ( Merremi. Indonesian Journal of Chemical Technology, 1(1), 30–37.
  15. Suryadi, A. M. A., Pakaya, M. S. Y., Djuwarno, E. N., Akuba, J., Farmasi, P. S., Olahraga, F., & Gorontalo, U. N. (2021). Penentuan Nilai Sun Protection Factor ( SPF ) Pada Ekstrak Kulit Buah Jeruk Nipis ( Citrus Aurantifolia ) Dengan Metode Spektrofotometri Uv-Vis Determination of sun protection factor ( SPF ) value in lime ( Citrus Aurantifolia ) peel extract using Uv-Vis . 3(2), 169–180.
  16. Syaputri, F. N., Mulya, R. A., Daru, T., Tugon, A., & Wulandari, F. (2023). Formulasi dan Uji Karakteristik Handbody Lotion y ang Mengandung Ekstrak. 4(1), 13–22.
  17. Widyastuti, & Desfita, D. (2020). Formulasi Lotion Ekstrak Etanol Buah Stroberi (Fragaria X ananassa Duchene Ex Weston) Sebagai Antioksidan Dan Tabir Surya. SCIENTA Jurnal Farmasi Dan Kesehatatan, 10(2), 120–127.
  18. Wintariani, N. P., & Lionita, N. K. V. (2023). Analisis Nilai Sun Protection Factor Krim Tabir Surya Ekstrak Tanaman Gonda ( Sphenoclea zeylanica Gaertner ) dengan Metode Spektrofotometri UV-Vis The SPF ( Sun Protection Factor ) Value Analysis of Gonda Plant ( Sphenoclea zeylanica Gaertner ). Jurnal Ilmiah Medicamento, 9(2), 90–95. https://doi.org/10.36733/medicamento.v9i2.6600