Main Article Content

Abstract

The rice field snail (Pila ampullaceae) is a member of the gastropod class commonly found in freshwater habitats and possesses a hard shell that protects its soft body. The shell of the rice field snail is known to be rich in CaCO3 compounds. In this study, the shell of the rice field snail is formulated into toothpaste as an abrasive material. Toothpaste is a semi-solid preparation that functions to remove dirt from the surface of teeth and maintain dental health. This study aims to determine the effect of hydroxypropyl methylcellulose (HPMC) concentration on the physical and hedonic properties of toothpaste based on rice field snail shell (Pila ampullaceae). Using a one shot case study design, three toothpaste samples with different HPMC concentrations, namely 3%, 4%, and 5%, were evaluated. The preparation evaluation included various physical property tests, such as organoleptic tests, homogeneity, pH, spreadability, viscosity, and foam height, as well as hedonic tests. The results of the study showed that variations in HPMC concentration affected several physical properties, including odor, spreadability, viscosity, and foam height. Among the three formulas tested, Formula 3 with a 5% HPMC concentration was the most preferred by respondents.

Keywords

Calcium carbonate (CaCO3) Hydroxypropyl methylcellulose (HPMC) Pila ampullaceae Rice field snail shell Toothpaste

Article Details

Author Biographies

Agnis Aditama, Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Wildan Hanifatul Adifa, Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Arifatul Muzayanah, Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Afifahtul Choiroh, Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Arine Giovani Kusumawardani, Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Ela Wahyuni, Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Pradiva Julias Tasya, Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Program Studi Farmasi, Politeknik Kesehatan Jember , Jember, Indonesia

Mikhania Christiningtyas Eryani, Program Studi Farmasi, Fakultas Farmasi, Universitas Jember, Jember, Indonesia

Program Studi Farmasi, Fakultas Farmasi, Universitas Jember, Jember, Indonesia

Faisal Akhmal Muslikh, Program Studi Farmasi, Fakultas Farmasi, Universitas Hang Tuah, Surabaya, Indonesia

Program Studi Farmasi, Fakultas Farmasi, Universitas Hang Tuah, Surabaya, Indonesia
How to Cite
Aditama, A., Adifa, W. H., Muzayanah, A., Choiroh, A., Kusumawardani, A. G., Wahyuni, E., Tasya, P. J., Eryani, M. C., & Muslikh, F. A. (2024). Formulation and Evaluation of Toothpaste Made from Rice Snail Shells (Pila ampullaceae) with Varying HPMC Concentrations. Borneo Journal of Pharmascientech, 8(2), 115-124. https://doi.org/10.51817/bjp.v8i2.533

References

  1. Ahmad, I. 2017. Pemanfaatan limbah cangkang kerang darah (Anadara granosa) sebagai bahan abrasif dalam pasta gigi. Jurnal Galung Tropika, 6(1), 49-59.
  2. Ansel, C.H. 1989. Pengantar Bentuk Sediaan Farmasi. Edisi 4. Ui Press. Jakarta.
  3. Aspinall, S. R., Parker, J. K., & Khutoryanskiy, V. V. 2021. Oral care product formulations, properties and challenges. Colloids and Surfaces B: Biointerfaces, 200, 111567.
  4. Cahnia, M. S., Muhaimin, M., Yuliawati, Y., & Sani K, F. 2022. Formulasi, Uji Efektivitas dan Uji Hedonik Masker Gel Peel Off Kombinasi Ekstrak Rimpang Kunyit (Curcuma longa L.) dan Madu (Mel depuratum) Sebagai Peningkat Elastisitas Kulit. Jurnal Ilmiah Kefarmasian Medical Sains, 7(2), 23-36.
  5. Dafal, G. B., & Khare, N. K. 2017. Formulation and evaluation of toothpaste by using eggshells. World Journal of Pharmaceutical Research, 6(2), 534-543.
  6. Delvita, H., & Djamas, D. 2015. The effect of calcination temperature variations on the characteristics of calcium carbonate (CaCO3) in the shells of rice field snails (Pila ampullacea) found in Pasaman Regency. Pillar Of Physics, 6(2).
  7. Depkes Rib. 2020. Sni 8861:2020 Pasta Gigi. Badan Standarisasi Nasional. Jakarta.
  8. Depkes Ric. 1995. Sni 12—3524-1995 Pasta Gigi. Badan Standarisasi Nasional. Jakarta.
  9. Ermawati, D. E., & Prilantri, H. U. 2019. Pengaruh Kombinasi Polimer Hidroksipropilmetilcelulosa dan Natrium Karboksimetilselulosa terhadap Sifat Fisik Sediaan Matrix-based Patch Ibupropen. J. Pharm Sci C, 2(1), 109-119.
  10. Juliantoni, Y., Subaidah, W. A., & Wirasisya, D. G. 2020. Formulasi Pasta Gigi Ekstrak Etanolik Herba Ashitaba (Angelica keiskei). Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice), 7(2), 70-73.
  11. Kemenkes RIa. 2018. Riset Kesehatan Dasar. Badan Penelitian Dan Pengembangan Tenaga Kesehatan Kemenkes. Jakarta.
  12. Kemenkes RIb. 2019. Infondatin Kesehatan Gigi Nasional. Kementerian Kesehatan Republik Indonesia, Jakarta.
  13. Kibbe, A.H. 2014. Handbook Of Pharmaceutical Excipients. Third Edition. Pharmaucetical Press. London.
  14. Lestari, U. Syamsurizal., Septima, NR 2020. Uji Aktivitas Pasta Gigi Arang Aktif Cangkang Sawit (Elaeis guineensis) Antiplak Pada Perokok Secara Invitro. SCIENTIA Jurnal Farmasi dan Kesehatan, 10(2), 177-186.
  15. Mahdalin, A., Widarsih, E., & Harismah, K. 2017. Pengujian sifat fisika dan sifat kimia formulasi pasta gigi gambir dengan pemanis alami daun stevia. URECOL, 135-138.
  16. Marlina, D., & Rosalini, N. 2017. Formulasi Pasta Gigi Gel Ekstrak Daun Sukun (Artocarpus Altilis) Dengannatrium Cmc Sebagai Gelling Agent Dan Uji Kestabilan Fisiknya. JPP (Jurnal Kesehatan Poltekkes Palembang), 12(1), 36-50.
  17. Nofriyanti. dan Lini, R. (2021). The Formulasi dan Uji Sifat Fisik Pasta Gigi Gel Dari Ekstrak Kering Jahe Merah (Zingiber officinale Roscoe Var. Rubrum): Formulation and Physical Properties Test Of Dry Extract Red Ginger In Gel Toothpaste (Zingiber officinale Roscoe Var. Rubrum). Jurnal Penelitian Farmasi Indonesia, 10(1), 6-11.
  18. Noval, N. Rosyifa, R. dan Annisa, A. 2019. Effect Of Hpmc Concentration Variation As Bahan Pengikat On Physical Stability Of Formulation Ethanol Extract Bundung Plants (Actinuscirpus grossus).
  19. Permadi, M. R., Oktafa, H., & Agustianto, K. 2019. Perancangan pengujian preference test, uji hedonik dan mutu hedonik menggunakan algoritma radial basis function network. SINTECH (Science and Information Technology) Journal, 2(2), 98-107.
  20. Riani, M., Darusman, F., & Suparman, A. 2020. Formulasi Sediaan Pasta Gigi Dari Ekstrak Daun Bidara Arab (Ziziphus Spina-Christi L.). Prosiding Farmasi, 6(2), 636-642.
  21. Rowee, R.C. Sheskey, P.J dan Quinn, M.E. 2009. Handbook Of Pharmaceutical Excipients. Edisi 6. Pharmaceutical Press And American Pharmacists Assosiation. London.
  22. Suryani, N., Betha, O. S., & Izzati, M. K. 2017. Suryani, N., Betha, O. S., & Izzati, M. K. 2017. Pengaruh HPMC terhadap sifat fisik sediaan masker peel-off ekstrak etanol kulit buah manggis (Garcinia mangostana L.). Medika Islamika. 14(2), 101-110.
  23. Syurgana, M. U., Febrina, L., & Ramadhan, A. M. 2017. Formulasi pasta gigi dari limbah cangkang telur bebek. In Proceeding of Mulawarman Pharmaceuticals Conferences (Vol. 6, pp. 127-140).
  24. Warnida, H., Juliannor, A., & Sukawaty, Y. 2016. Formulasi pasta gigi gel ekstrak etanol bawang dayak (Eleutherine bulbosa (Mill.) Urb.). JSFK (Jurnal Sains Farmasi & Klinis), 3(1), 42-49.
  25. Yuliastri, W. O., & Prasetyo, M. 2019. Formulasi pasta gigi herbal ekstrak daun sukun (Artocarpus altilis) dan uji aktivitas antibakteri terhadap bakteri Streptococcus mutans. Jurnal Mandala Pharmacon Indonesia, 5(01), 10-14.